Method for producing cytosine nucleoside compounds
US7629457B2 · kind B2 · utility
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3References
3Claims
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Assignee
Inventors
Key dates
| Filing date | Oct 19, 2004 |
| Grant date | Dec 8, 2009 |
| Priority date | — |
| Expiry date | Oct 19, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P19/385
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides a method for producing a cytosine nucleoside compound from pentose-1-phosphate and cytosine or a derivative thereof using a nucleoside phosphorylase reactive to cytosine or a bacterium having the enzyme activity. The invention also provides a method for specifically reducing an activity to degrade the substrates or the product, resulting in efficient production of the cytosine nucleoside compound. According to the invention, little by-product is produced in producing cytonucleocide compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.