High performance liquid chromatography with an aqueous mobile phase for analysis of drug and its metabolite
US7632656B2 · kind B2 · utility
14Cited by
2References
15Claims
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Key dates
| Filing date | Mar 4, 2004 |
| Grant date | Dec 15, 2009 |
| Priority date | — |
| Expiry date | Jul 6, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6893
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The amount of drug consumption caused by a specific drug-metabolizing enzyme and/or the amount of the resulting metabolite(s) is measured by chromatography with an aqueous mobile phase under temperature control using a packing material whose surface is coated with a polymer having a hydration force varying in the temperature range of 0° C. to 80° C. This system enables proper evaluation of drug-metabolizing capacity through simple means without adversely affecting the environment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.