Use of calmodulin kinase II inhibitors to treat myocardial dysfunction in structural heart disease
US7632815B2 · kind B2 · utility
3Cited by
2References
20Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 13, 2007 |
| Grant date | Dec 15, 2009 |
| Priority date | — |
| Expiry date | May 12, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method for treating structural heart disease in a subject, comprising administering an effective amount of an inhibitor of CaMKII to the subject, whereby the administration of the inhibitor treats the structural heart disease in the subject. Also provided are transgenic animal models for treating structural heart disease. Further provided is a means of screening for a compound that can treat structural heart disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.