Anti-cancer phosphine containing [AuIIIm(CNC)mL]n+ complexes and derivatives thereof and methods for treating cancer using such compositions
US7632827B2 · kind B2 · utility
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Key dates
| Filing date | Dec 20, 2007 |
| Grant date | Dec 15, 2009 |
| Priority date | — |
| Expiry date | Dec 20, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K33/243
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Gold(III) phosphine complexes [Aum(CNC)mL]n+ (where HCNCH=2,6-diphenylpyridine) and their use as anti-tumor agents are disclosed. Notable results for the appearance of new potential anti-tumor application of these gold(III) complexes are reported. The described complexes show promising cytotoxic properties toward cancer cells in both in vitro and in vivo studies.
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