Osteoprotegerin
US7632922B1 · kind B1 · utility
0Cited by
3References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 22, 2000 |
| Grant date | Dec 15, 2009 |
| Priority date | — |
| Expiry date | May 20, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/7151
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention discloses a novel secreted polypeptide, termed osteoprotegerin, which is a member of the tumor necrosis factor receptor superfamily and is involved in the regulation of bone metabolism. Also disclosed are nucleic acids encoding osteoprotegerin, polypeptides, recombinant vectors and host cells for expression, antibodies which bind OPG, and pharmaceutical compositions. The polypeptides are used to treat bone diseases characterized by increased resorption such as osteoporosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.