Patent · US Expired

Inhibitors of integrin ανβ6

US7632951B2 · kind B2 · utility

1Cited by

3References

26Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Oliver Schadt · Rodenbach, DE
Alfred Jonczyk · Darmstadt, DE
Wolfgang Staehle · Ingelheim am Rhein, DE
Simon Goodman

Key dates

Filing date	Feb 21, 2002
Grant date	Dec 15, 2009
Priority date	—
Expiry date	Feb 21, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D409/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Novel biphenyl derivatives of the general formula (I) in which R1, R1′, R1″, R2, R2′, R3 and n are as defined in claim 1, their stereoisomers and their physiologically acceptable salts or solvates are novel integrin inhibitors which preferentially inhibit the αvβ6 integrin receptor. The novel compounds can be used, in particular, as medicaments.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.