Ultrahigh-pressure dual on-line solid phase extraction/capillary reverse-phase liquid chromatography system
US7637147B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 1, 2007 |
| Grant date | Dec 29, 2009 |
| Priority date | — |
| Expiry date | May 29, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/347
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An ultrahigh-pressure dual on-line solid phase extraction/capillary reverse-phase liquid chromatography (DO-SPE/cRPLC) system is provided. The system comprises: a sample loading valve into which a first solvent and a sample to be analyzed are loaded; a first column valve in flow communication with a first solid-phase extraction column and a first reverse-phase liquid chromatography column; a second column valve in flow communication with a second solid-phase extraction column and a second reverse-phase liquid chromatography column; a column-switching valve for determining whether the sample is transferred to either the first column valve or the second column valve; a solvent selection valve in flow communication with the first and second column valves to supply the first solvent or a mixed solvent of the first solvent and a second solvent to the first and second column valves; a second solvent loading valve, in flow communication with a solvent mixer, into which the first and second solvents are loaded; a supply pump for loading the second solvent into the second solvent loading valve; and a supply pump for loading the first solvent into the sample loading valve, the second solvent…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.