Crystalline compounds

US7638625B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Uwe Ries · Biberach an der Riß, DE
• Guenther Huchler · Biberach an der Riß, DE
• Sonja Sproll · Ochsenhausen, DE
• Ulrike Werthmann · Biberach an der Riß, DE
• Andreas Zopf · Wassertrüdingen, DE

Key dates

• Filing date: Apr 12, 2007
• Grant date: Dec 29, 2009
• Expiry date: Oct 21, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to the new crystalline compounds A of general formula Iwherein A1, A2, A3, X, Y1, Y2 and Y3 are defined as in claim 1, and which are present in the form of their physiologically acceptable salts with acids, the acids being selected from the group B comprising hydrochloric acid, hydrobromic acid, sulphuric acid, phosphoric acid, benzenesulphonic acid, p-toluenesulphonic acid, maleic acid, succinic acid, fumaric acid, D-(−)-tartaric acid, L-(+)-tartaric acid, naphthalene-2-sulphonic acid and naphthalene-1,5-disulphonic acid, and the polymorphs, the corresponding solvates and hydrates thereof.