Methods and apparatus for complex genetics classification based on correspondence analysis and linear/quadratic analysis
US7640113B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 2, 2002 |
| Grant date | Dec 29, 2009 |
| Priority date | — |
| Expiry date | Dec 2, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B40/00
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Methods and apparatus for use in complex genetics classification are disclosed. In one illustrative example, a method is performed using data from a sample population which includes counts of individuals in the sample population associated with both a particular diploid haplotype pair and a particular genetic trait class. A correspondence to analysis (COA) on the data from the sample population is performed (at least in part) so as to determine a first plurality of n-dimensional coordinates for each diploid haplotype pair and a second plurality of n-dimensional coordinates for each genetic trait class. A linear or quadratic classification analysis is then performed based on the first and the second pluralities of n-dimensional coordinates and diploid haplotype pairs of the at least two genes from an individual sample. Advantageously, the individual sample can be accurately classified into one of the genetic trait classes using the method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.