Rapid-heating drug delivery article and method of use
US7645442B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 4, 2003 |
| Grant date | Jan 12, 2010 |
| Priority date | — |
| Expiry date | Feb 1, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2205/50
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A device, method, and system for producing a condensation aerosol are disclosed. The device includes a chamber having an upstream opening and a downstream opening which allow gas to flow through the chamber, and a heat-conductive substrate located at a position between the upstream and downstream openings. Formed on the substrate is a drug composition film containing a therapeutically effective dose of a drug when the drug is administered in aerosol form. A heat source in the device is operable to supply heat to the substrate to produce a substrate temperature greater than 300° C., and to substantially volatilize the drug composition film from the substrate in a period of 2 seconds or less. The device produces an aerosol containing less than about 10% by weight drug composition degradation products and at least 50% of the drug composition of said film.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.