Alpha-enolase specific antibody and method of use
US7645453B2 · kind B2 · utility
4Cited by
1References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 29, 2006 |
| Grant date | Jan 12, 2010 |
| Priority date | — |
| Expiry date | Dec 29, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/988
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention relates to a method of monitoring cancer development by determining the abundance of alpha-enolase protein wherein increased abundance is an indication of the severity of cancer. In another embodiment, the invention relates to a method of detecting cancer malignancy by determining the abundance of alpha-enolase antibodies in a sample wherein low levels of such antibodies indicates the malignancy of cancer. Also provided is a method of suppressing tumor growth by inducing the anti-ENO1 immune response.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.