Patent · US Active

Method for producing optically active N-protected-propargylglycine

US7645607B2 · kind B2 · utility

0Cited by
1References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 20, 2006
Grant dateJan 12, 2010
Priority date—
Expiry dateJan 26, 2027

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P13/04
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A method for producing (S)—N-protected-propargylglycine of the following formula (2), wherein the method comprises asymmetrically hydrolyzing an N-protected-propargylglycine ester of the following formula (1) by using an asymmetric hydrolysis enzyme or a cultured substance of a microorganism having an ability of producing this enzyme or a treated substance thereof.The hydrolysis enzyme is obtained from a microorganism selected from the group consisting of Thermomyces genus, Aspergillus genus, Rhizopus genus, Penicillium genus, Pseudomonas genus, Humicola genus, Burkholderia genus, Candida genus Bacillus genus and Streptomyces genus.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.