Methods of indentifying modulators of the FGF receptor
US7645857B2 · kind B2 · utility
21Cited by
1References
2Claims
0Family size
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Key dates
| Filing date | Jul 18, 2005 |
| Grant date | Jan 12, 2010 |
| Priority date | — |
| Expiry date | Dec 29, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B15/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides fragments of SNT and FGFR which can form a binding complex that is amenable to structural determinations by NMR spectroscopy. The three-dimensional structural data is also included as part of the invention. In addition, the present invention provides methodology for related structure based rational drug design using the three-dimensional data. Nucleotide and amino acid sequences of the fragments are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.