Inhibitor of protein modification products formation
US7645882B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Dec 3, 2004 |
| Grant date | Jan 12, 2010 |
| Priority date | — |
| Expiry date | Jul 12, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D231/54
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
To provide a inhibitor of protein modification products formation capable of inhibiting of vitamin B6 deficiency disease as a side effect, especially a renal protective agent.There is provided a use, as an active ingredient, of any of free or salt-form compounds of either of the formulae: (I) (II) [wherein R1 is substituted or unsubstituted aromatic ring; and each of R2, R3 and R4 is a hydrogen atom or monovalent organic group, or alternatively R2 and R3 cooperate to form a condensed ring or R3 and R4 cooperate to represent a divalent organic group, provided that R3 and R4 are not simultaneously hydrogen atoms].
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.