Method for hydrogenation of α, β-unsaturated carbonyl compounds

US7645908B2 · kind B2 · utility

Assignee

• Studiengesellschaft Kohle gGmbH · DE

Inventors

• Benjamin List · Wetter (Ruhr), DE
• Jung Woon Yang · Busan, KR

Key dates

• Filing date: Sep 27, 2005
• Grant date: Jan 12, 2010
• Expiry date: Oct 3, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A method for the chemoselective hydrogenation of α, β unsaturated carbonyl compounds is disclosed, in which compounds of the formula R4R3C═CR2—C(O)R1, wherein R1—R4 are as defined herein, are reacted with a hybrid donor to form a compound of formula R4R3CH—CH(R2)—C(O)R1, in which R1—R4 are as above. That method permits the selective hydrogenation of α, β unsaturated aldehydes and ketones without the use of metal catalysts.