Cell lysis method by immobilized metal-ligand complex
US7648838B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 4, 2005 |
| Grant date | Jan 19, 2010 |
| Priority date | — |
| Expiry date | Jun 6, 2027 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/25
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided is a lysis method for cells or viruses, including: immobilizing a metal-ligand complex on a solid support; and mixing the complex immobilized on the support with a cell or virus solution. According to the lysis method, by immobilizing a chemical on a solid support to perform cell lysis, the dilution problem according to the addition of a cell lysis solution can be resolved and a separate process of removing the chemical is not required so as to reduce the steps upon LOC implementation. In addition, since a variety of solid supports, such as chips, beads, nanoparticles etc. can be used, cell lysis apparatuses of various forms can be fabricated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.