Methods and compositions for the treatment of diseases of the eye

US7648959B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Hans-Markus Bender · Birkenfeld, DE
• Jutta Haunschild · Birkenfeld, DE
• Matthias Wiesner · Seeheim-Jugenheim, DE
• Ulrich Lang · San Francisco, US
• Martin Friedlander · Del Mar, US

Key dates

• Filing date: Jun 7, 2006
• Grant date: Jan 19, 2010
• Expiry date: Sep 26, 2026

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Methods and compositions for prophylaxis and/or treatment of diseases of the eye of a patient resulting angiogenesis in the eye using antagonists of the integrin receptors αv β3 and/or αv β5. The compositions can be nanoparticles and are administered to the eye by injection into the sclera of the eye.