Bicyclic protein kinase inhibitors

US7648987B2 · kind B2 · utility

Assignee

• OSI Pharmaceuticals, LLC · US

Inventors

• Andrew Philip Crew · North Babylon, US
• Han-Qing Dong · Farmingdale, US
• Mark J. Mulvihill · Melville, US
• Douglas S. Werner · West Palm Beach, US
• Mridula Kadalbajoo · Farmingdale, US
• Radoslaw Laufer · Oakville, CA

Key dates

• Filing date: Dec 4, 2006
• Grant date: Jan 19, 2010
• Expiry date: Dec 4, 2026

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the Formulaand pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit protein kinase enzymes and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system.