39-desmethoxy derivatives of rapamycin
US7648996B2 · kind B2 · utility
7Cited by
33References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 10, 2006 |
| Grant date | Jan 19, 2010 |
| Priority date | — |
| Expiry date | Jul 22, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel 39-desmethoxyrapamycin derivatives, methods for their production, and uses thereof. In a further aspect the present invention provides for the use of these 39-desmethoxyrapamycin derivatives in the treatment of cancer and/or B-cell malignancies, the induction or maintenance of immunosuppression, the treatment of transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation, vascular disease and fibrotic diseases, the stimulation of neuronal regeneration or the treatment of fungal infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.