Biodegradable oxidized cellulose esters and their uses as microspheres
US7649089B2 · kind B2 · utility
130Cited by
10References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 28, 2004 |
| Grant date | Jan 19, 2010 |
| Priority date | — |
| Expiry date | Dec 18, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B15/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new cellulose excipient, OCCAE, suitable for use as a binder, filler, and/or disintegrant in the development of solid dosage forms and as a bodying agent or a drug carrier in the preparation of topical formulations is described. The cellulose excipient is formed by reacting an oxidized cellulose ester with an alcohol in the presence of a catalyst. The invention also describes the formation of controlled release microspheres using OCCAE and/or oxidized cellulose esters that may be used to control the release of drug in a patient over a time period of several hours to several days.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.