Prolonged release bioadhesive therapeutic systems
US7651698B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 25, 2005 |
| Grant date | Jan 26, 2010 |
| Priority date | — |
| Expiry date | May 19, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2063
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention concerns a prolonged release bioadhesive mucosal therapeutic system containing at least one active principle, with an active principle dissolution test of more than 70% over 8 hours and to a method for its preparation. This bioadhesive therapeutic system comprises quantities of natural proteins representing 50% by weight of active principle and at least 20% by weight of said tablet, between 10% and 20% of a hydrophilic polymer, and compression excipients, and comprising between 4% and 10% of an alkali metal alkylsulphate to reinforce the local availability of active principle and between 0.1% and 1% of a monohydrate sugar.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.