Prenatal diagnosis method on isolated foetal cell of maternal blood
US7651838B2 · kind B2 · utility
Assignees
Inventor
Key dates
| Filing date | Oct 30, 2003 |
| Grant date | Jan 26, 2010 |
| Priority date | — |
| Expiry date | Oct 30, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/368
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention concerns a novel non-invasive prenatal diagnostic method implemented with a sample of maternal blood. Said method enables prenatal diagnosis on isolated non-apoptotic epithelial foetal cells of maternal blood after they have been enriched by filtration, morphologically or immunologically and genetically analysed. Said method is advantageous in that it is perfectly harmless for the mother and the foetus and provides a highly sensitive and specific diagnosis. It enables early detection of a genetic or chromosomal abnormality of the foetus, of a genetic or infectious (viral, bacterial or parasitic) pathology of the foetus, of accurate genotype, and in particular of the genetic sex of the foetus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.