Absorption enhancers such as e.g. BHT, BHA or propyl gallate
US7651995B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Apr 15, 2004 |
| Grant date | Jan 26, 2010 |
| Priority date | — |
| Expiry date | Apr 15, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/4891
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a pharmaceutical composition comprising a mixture of (a) an active macromolecular principle, and (b) an aromatic alcohol absorption enhancer chosen from butylated hydroxy toluene, butylated hydroxy anisole and analogues and derivatives thereof, wherein the aromatic alcohol absorption enhancer is present in an amount by weight greater than or equal to that of the active macromolecular principle, and further comprises a pharmaceutical composition comprising a mixture of (a) an active macromolecular principle, (b) an aromatic alcohol absorption enhancer chosen from propyl gallate, butylated hydroxy toluene, butylated hydroxy anisole and analogues and derivatives thereof, wherein the aromatic alcohol absorption enhancer is present in an amount by weight greater than or equal to that of the active macromolecular principle, and (c) a solubilisation aid capable of increasing the solubility of the aromatic alcohol absorption enhancer in aqueous media.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.