Patent · US Active

Substituted 6-cyclohexylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(ADP-ribose) polymerase inhibitors

US7652014B2 · kind B2 · utility

14Cited by

1References

28Claims

0Family size

Assignee

Janssen Pharmaceuticals, Inc. · BE

Inventors

Dominique Jean-Pierre Mabire · La Saussaye, FR
Jacobus Alphonsus Josephus Van Dun · Kasterlee, BE
Maria Victorina Francisca Somers · Vosselaar, BE
Walter Boudewijn Leopold Wouters · Kapellen, BE

Key dates

Filing date	Nov 18, 2004
Grant date	Jan 26, 2010
Priority date	—
Expiry date	Jul 12, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I)wherein n, s, R1, R2, R3, Q, X and Y have defined meanings.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.