Methods and compositions for vaccination against or involving enterobacteriaceae bacteria
US7655241B2 · kind B2 · utility
0Cited by
5References
26Claims
0Family size
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Key dates
| Filing date | Mar 20, 2003 |
| Grant date | Feb 2, 2010 |
| Priority date | — |
| Expiry date | Jul 13, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention concerns the use of methods and compositions to prophylactically or therapeutically vaccinate a subject against a pathogen or disease. Embodiments of the invention include the production of an attenuated bacterium from the family Enterobacteriaceae with a non-functional lipoprotein for use as a vaccine or as a vaccine vector for delivering antigens to a subject to be vaccinated. In certain embodiments, a bacterium of the Enterobacteriaceae family lacking a wild type LP, for example Salmonella typhimurium lacking a wild type LP, may be produced and used as a vaccine or vaccine vector.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.