Biomimetic of Evodia rutaecarpa fruit extract for amelioration of inflammation
US7655659B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Aug 11, 2005 |
| Grant date | Feb 2, 2010 |
| Priority date | — |
| Expiry date | Mar 28, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods are provided for reversing and/or inhibiting inflammation, e.g., by inhibiting prostaglandin and/or COX-2 production, using one or more indolequinazoline alkaloids, preferably in combination with butylated hydroxytoluene. The preferred indolequinazoline alkaloids are rutaecarpine, evodiamine, and dehydroevodiamine, which are naturally found in unpurified form in the traditional Chinese medicine Wu Chu Yu made from the fruit of the herb, Evodia rutaecarpa.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.