Integrated microfluidic transport and sorting system
US7658829B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Oct 25, 2005 |
| Grant date | Feb 9, 2010 |
| Priority date | — |
| Expiry date | Feb 4, 2028 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB03C2201/26
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The invention integrates a two-stage dielectrophoretic (DEP) droplet dispensing and distribution system with particulate DEP to create a novel LOC platform capable of manipulating biological cells based on the varied dielectrophoretic signatures that distinguish cells in a population, for example, healthy from diseased cells. The two-stage DEP droplet transport system acts as the backbone of this application, providing the essential dispensing and distribution function, while particulate DEP provides the critical capability to characterize and analyze the heterogeneous biological cell populations routinely encountered in biotechnology and clinical settings.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.