Surface modification of lactose excipient for use in powders for inhalation

US7658949B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Michael Trunk · Ingelheim am Rhein, DE
• Inga-Lis Timmermann · Kiel, DE
• Bernd Mueller · Ludwigshafen, DE
• Hartwig Steckel · Kiel, DE

Key dates

• Filing date: Sep 21, 2005
• Grant date: Feb 9, 2010
• Expiry date: Oct 3, 2026

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K47/26
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a process for the surface-energy passivation of lactose which is intended for use as an excipient in the production of inhalable powders, and the use of such optimised carrier materials in the manufacture of inhalable powders.