Method for the diagnosis of sepsis with determination of soluble cytokeratin fragments
US7659075B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Nov 29, 2002 |
| Grant date | Feb 9, 2010 |
| Priority date | — |
| Expiry date | Jun 2, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/811
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Method for early differential diagnosis and detection, for prognosis and assessment of the severity and for therapy-accompanying assessment of the course of sepsis and sepsis-like systemic infections, in which, preferably with additional determination of at least one further parameter suitable for sepsis diagnosis, the amount of soluble cytokeratin fragments, in particular of CYFRA 21-1, TPS, TPA and/or sCY1F, in a biological fluid of a patient in whom a sepsis is present or a sepsis is suspected is determined and conclusions with regard to the presence, the expected course, the severity and/or the success of initiated measures for the therapy of the sepsis are drawn from the determined amount of soluble cytokeratin fragments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.