Methods utilizing target genes related to immune-mediated diseases
US7659077B2 · kind B2 · utility
1Cited by
1References
5Claims
0Family size
Inventors
Key dates
| Filing date | Mar 17, 2004 |
| Grant date | Feb 9, 2010 |
| Priority date | — |
| Expiry date | Mar 17, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/505
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides methods utilizing novel target genes related to immune-mediated diseases, such as asthma, allergy and autoimmune diseases. The invention is based on a molecular level description of the polarization of CD4+ precursor cells (Thp) from which T helper cells are known to originate. Particularly, the present invention provides a method of identifying a compound capable of modulating the polarization of CD4+ lymphocytes. The invention is also related to a method for assessing the presence of, or a predisposition to, an immune-related disorder in a subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.