Patent · US Expired

Treatment of osteoarthritis

US7659246B2 · kind B2 · utility

0Cited by

1References

19Claims

0Family size

Assignee

Promics PTY Limited · AU

Inventors

Ian Alexander Shiels · Ipswich, AU
David Fairlie · Faulconbridge, AU

Key dates

Filing date	Oct 15, 2003
Grant date	Feb 9, 2010
Priority date	—
Expiry date	Oct 15, 2023

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates to methods of treatment of osteoarthritis, and especially to treatment of this condition with cyclic peptidic and peptidomimetic compounds which have the ability to modulate the activity of G protein-coupled receptors. The compounds preferably act as antagonists of the C5a receptor, and are active against C5a receptors on polymorphonuclear leukocytes and macrophages. Particularly preferred compounds for use in the invention are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.