Radiolabelled benzamide analogues, their synthesis and use in diagnostic imaging
US7659400B2 · kind B2 · utility
3Cited by
3References
10Claims
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Key dates
| Filing date | Jun 1, 2007 |
| Grant date | Feb 9, 2010 |
| Priority date | — |
| Expiry date | Apr 11, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/13
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Fluoroalkoxybenzamide compounds which selectively bind Sigma-2 receptors are disclosed. These compounds, when labelled with 18F, can be used as radiotracers for imaging of tumors by positron emission tomography (PET). In addition, these compounds, when labelled with 123I, can be used as radiotracers for imaging of tumors by single photon emission computed tomography (SPECT). Methods for synthesis of these compounds are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.