Selective high affinity polydentate ligands and methods of making such
US7662785B2 · kind B2 · utility
2Cited by
14References
19Claims
0Family size
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Key dates
| Filing date | Feb 9, 2005 |
| Grant date | Feb 16, 2010 |
| Priority date | — |
| Expiry date | Oct 11, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/574
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.