Use of antisense oligonucleotides or siRNA to suppress expression of eIF-5A1
US7662796B2 · kind B2 · utility
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Key dates
| Filing date | Nov 28, 2005 |
| Grant date | Feb 16, 2010 |
| Priority date | — |
| Expiry date | Oct 8, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis factor 5A1 or simply factor 5A1, apoptosis factor 5A1 nucleic acids and polypeptides and methods for inhibiting or suppressing apoptosis in cells using antisense nucleotides or siRNAs to inhibit expression of factor 5A1. The invention also relates to suppressing or inhibiting expression of pro-inflammatory cytokines by inhibiting expression of apoptosis factor 5A.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.