Patent · US Active

Pyrazole derivatives having tyrosine kinase inhibitory activity

US7662827B2 · kind B2 · utility

1Cited by

0References

9Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Guenter Hoelzemann · Seeheim-Jugenheim, DE
Helene Crassier · Darmstadt, DE
Wilfried Rautenberg · Reinheim, DE

Key dates

Filing date	Jul 24, 2006
Grant date	Feb 16, 2010
Priority date	—
Expiry date	Jul 24, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds of the formula (I), in which R, X, R1, R2, R3 and R4 have the meanings indicated in Claim (1), are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and can be employed, inter alia, for the treatment of tumours.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.