Peptides having protected amines of untargeted sites, methods for production thereof and of specifically conjugated PEG peptides using the same
US7662915B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Jan 18, 2003 |
| Grant date | Feb 16, 2010 |
| Priority date | — |
| Expiry date | Dec 6, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/064
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to synthetic peptides having selectively protected amines of untargeted sites and to methods for production thereof and for specifically conjugating PEG to targeted sites of the synthetic peptides using the same. The present invention provides a much higher yield of PEG conjugated peptides in which PEG is specifically combined to amines at targeted sites.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.