Liver disease-related methods and systems

US7668661B2 · kind B2 · utility

Assignee

• Siemens Healthcare Diagnostics Inc. · US

Inventors

• Michael Volker
• Michael Becka · Neheim, DE
• Werner Kroll · Solingen, DE
• Andreas M. Knorr · Erkrath, DE
• Sylvia Unger · Heidelberg, DE
• Mathias Gehrmann · Tönisvorst, DE
• Guido Hennig · Wynau, CH
• Elmar Burchardt · Wuppertal, DE
• Michael Arthur · Romsey, GB
• Alastair D. Burt · Rothbury, GB
• Massimo Pinzani · Scandicci, IT
• Detlef Schuppan · Mainz, DE
• Robert P. Thiel · Bethany, US
• Christoph Petry · Cologne, DE
• William Rosenberg · Eastleigh, GB

Key dates

• Filing date: Jun 15, 2004
• Grant date: Feb 23, 2010
• Expiry date: Sep 28, 2025

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A90/10
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention provides diagnostic methods, kits, and systems, and related computer-readable media, which use multiple blood marker values, including serum and plasma marker values, to aid in the diagnosis of the status or progress of a liver disease in a patient.The invention also provides methods and systems, and related computer-readable media, that use blood marker values, including serum and plasma marker values: (1) to screen for active ingredients useful in the treatment of a liver disease; (2) to aid in the selection of treatment regimens for patients that are predisposed to, or suffer from, liver disease; and (3) to aid in the design of clinical programs useful in monitoring the status or progress of liver disease in one or more patients.