Method for analyzing dynamic detectable events at the single molecule level
US7668697B2 · kind B2 · utility
55Cited by
72References
28Claims
0Family size
Inventors
Key dates
| Filing date | Feb 6, 2007 |
| Grant date | Feb 23, 2010 |
| Priority date | — |
| Expiry date | Feb 6, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6439
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method to be implemented on or in a computer is disclosed, where the method includes data collection, calibration, candidate selection, and analysis of data streams associated with each candidate to classify single molecule fluorescence resonance energy transfer events. Once classified, the classification can be related to the nature of the events, such as the identification of dNTP incorporation during primer extension to obtain a base read out of an unknown template.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.