Systems and methods for delivering drugs to selected locations within the body
US7670329B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 15, 2006 |
| Grant date | Mar 2, 2010 |
| Priority date | — |
| Expiry date | Aug 15, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2025/1052
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A transvascular system (10) for delivering a drug to a tissue region from a blood vessel, such as a coronary vein, includes a catheter (12) having a distal portion (26) with puncturing (14), orientation (16), drug delivery (62), and imaging elements (18). The puncturing element (14) is deployable for penetrating the vessel wall to access the tissue region. The orientation element (16), e.g. a “cage” including a plurality of struts (38) (40) and/or a radiopaque marker, has a predetermined relationship with the puncturing element (14), the imaging element (18) detecting the location of the orientation element (16) with respect to the tissue region to orient the puncturing element. The catheter (12) is percutaneously introducing into the vessel, the puncturing element (14) is oriented towards the tissue region, the puncturing element (14) is deployed to access the tissue region, and the drug is delivered to the tissue region. An ablation device (230) may also be deployed to create a cavity or fluid reservoir in the tissue region for receiving the drug therein, or an indwelling catheter (214) may be advanced into and left in the tissue region.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.