Patent · US Active

Human DNAX toll-like receptor 4 proteins, related reagents and methods

US7670603B2 · kind B2 · utility

2Cited by

2References

3Claims

0Family size

Assignee

SCHERING CORPORATION · US

Inventors

Gerard T. Hardiman · San Diego, US
Fernando Rock · Los Altos, US
J. Fernando Bazan · Menlo Park, US
Robert A. Kastelein · Portola Valley, US
Stephen Ho · New York, US
Yong-Jun Liu · Oakville, CA

Key dates

Filing date	Apr 9, 2008
Grant date	Mar 2, 2010
Priority date	—
Expiry date	Apr 9, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Nucleic acids encoding mammalian Toll-like receptors (TLRs) have been identified in human cells. Recombinantly produced TLRs are used in the preparation of antibodies that are capable of binding to the TLRs. The antibodies are advantageously used in the prevention and treatment of septic shock, inflammatory conditions, and viral infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.