Androgen modulators

US7670613B2 · kind B2 · utility

Assignee

• PFIZER INC. · US

Inventors

• Lain-Yen Hu · Ann Arbor, US
• Bruce Lefker · Gales Ferry, US
• Daniel Y. Du · Milan, US
• Yvonne Dorothy Smith · Ypsilanti, US
• Huangshu Lei · Ann Arbor, US
• William Harter · Chelsea, US
• Victoria Leigh Downs · Pinckney, US
• Mark Laurence Boys · Lyons, US
• Donna Iula · Ann Arbor, US

Key dates

• Filing date: Jul 5, 2005
• Grant date: Mar 2, 2010
• Expiry date: Dec 30, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/42
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is directed to a new class of 4-cycloalkoxy benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.