Sequential drug delivery systems
US7670617B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 8, 2004 |
| Grant date | Mar 2, 2010 |
| Priority date | — |
| Expiry date | Nov 27, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/48
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to methods and composition for improving absorption and dissolution of active ingredients of drugs. The invention provides a method of administration of an active ingredient to a mammal through a transmucosal route that includes delivering the active ingredient to a desired site in a body of the mammal, and, sequentially, at the desired site, promoting dissolution and absorption of the active ingredient. In a preferred embodiment, the pH of the localized environment of the active ingredient is sequentially modified to promote dissolution and absorption.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.