pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients
US7670627B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 9, 2002 |
| Grant date | Mar 2, 2010 |
| Priority date | — |
| Expiry date | Jul 1, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/5084
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a novel pH triggered, targeted controlled release system. The controlled delivery system of the present invention is substantially a free-flowing powder formed of solid hydrophobic nano-spheres comprising pharmaceutical active ingredients that are encapsulated in a pH sensitive micro-spheres. The invention also relates to the processes for preparing the compositions and processes for using same. The controlled release system can be used to target and control the release of pharmaceutical active ingredients onto certain regions of the gastrointestinal tract including the stomach and the small intestine. The invention further pertains to pharmaceutical products comprising the controlled release system of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.