Methods of diagnosing tissue fibrosis
US7670764B2 · kind B2 · utility
14Cited by
5References
46Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 22, 2004 |
| Grant date | Mar 2, 2010 |
| Priority date | — |
| Expiry date | May 6, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a method of diagnosing the presence or severity of tissue fibrosis in an individual by detecting α2-macroglobulin (α2-MG) in a sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissue inhibitor of metalloproteinases-1 (TIMP-1) in a sample from the individual; and diagnosing the presence or severity of tissue fibrosis in the individual based on the presence or level of α2-MG, HA and TIMP-1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.