Method for detecting DNA methylation using labelled S-adenosylmethionine analogs
US7670777B2 · kind B2 · utility
2Cited by
5References
9Claims
0Family size
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Key dates
| Filing date | Sep 26, 2007 |
| Grant date | Mar 2, 2010 |
| Priority date | — |
| Expiry date | Sep 26, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6827
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a method for detecting the methylation status in DNA samples. According to the invention, a DNA methyl transferase and a labeled S-adenosylmethionine derivative allow a detectable label to be covalently bonded to the DNA, in accordance with the respective methylation status of the DNA sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.