Sulfonylguanidine compounds and pharmaceutical uses thereof

US7671074B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Matthias Gerlach · Wächtersbach, DE
• Heinz Uragg · Stolberg, DE
• Michael Haurand · Aachen, DE
• Claudia Puetz · Lehrte, DE
• Corinna Sundermann · Aachen, DE
• Boris Chizh · Aachen, DE

Key dates

• Filing date: May 1, 2007
• Grant date: Mar 2, 2010
• Expiry date: May 1, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Sulfonylguanidine compounds corresponding to the tautomeric formulas I and Ia, a method for producing them, pharmaceutical compositions containing them, and methods of using them to prepare medicaments and for treating various medical conditions. The sulfonylguanidine compounds have an affinity for the gabapentin binding site and can be used to treat conditions such as pain, epilepsy, migraine and others.