Patent · US Active

Arylamino-arylpropanolamine derivatives and methods of their use

US7671238B2 · kind B2 · utility

0Cited by

1References

19Claims

0Family size

Assignee

Wyeth, LLC · US

Inventors

An Thien Vu · Pottstown, US
Stephen Todd Cohn · Reading, US
Eugene A. Terefenko · Quakertown, US
William J. Moore · Hagerstown, US
Puwen Zhang · Audubon, US
Paige Erin Mahaney · West Orange, US
Eugene J. Trybulski · Princeton Junction, US

Key dates

Filing date	Oct 2, 2007
Grant date	Mar 2, 2010
Priority date	—
Expiry date	Jan 22, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C217/84
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is directed to arylamino-arylpropanolamine derivatives of formula I:or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromyalgia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.