Methods and compositions for blood pool identification, drug distribution quantification and drug release verification
US7672704B2 · kind B2 · utility
6Cited by
15References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 11, 2003 |
| Grant date | Mar 2, 2010 |
| Priority date | — |
| Expiry date | Jun 8, 2027 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods and compositions useful for detecting an in vivo blood pool, monitoring the distribution of a compound of interest to a desired site in an organism by magnetic resonance imaging, monitoring the accumulation of a compound of interest at a desired site in vivo by magnetic resonance imaging, and monitoring the release of liposomal contents to an external stimulus at a desired site in vivo by magnetic resonance imaging are disclosed. Some compositions comprise envirosensitive or non-sensitive liposomes. Contrast agents, such as manganese-based compounds, are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.