Methods for enhancing neuroprotection via administration of stem cells and blood brain barrier permeabilizers
US7674457B2 · kind B2 · utility
14Cited by
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20Claims
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Key dates
| Filing date | Dec 15, 2004 |
| Grant date | Mar 9, 2010 |
| Priority date | — |
| Expiry date | Jan 5, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2239/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods for enhancing the neuroprotective effect of umbilical cord blood cells. More particularly, the present invention provides methods of treating neurodegenerative disorders by administering umbilical cord blood cells and a substance capable of permeabilizing the blood brain barrier. In one embodiment, the blood brain barrier permeabilizer is mannitol. In another embodiment, the blood brain barrier permeabilizer is Cereport.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.