Formulations and methods of using nitric oxide mimetics against a malignant cell phenotype
US7678391B2 · kind B2 · utility
38Cited by
22References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 6, 2003 |
| Grant date | Mar 16, 2010 |
| Priority date | — |
| Expiry date | Dec 14, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods and formulations for inhibiting, treating and preventing a malignant cell phenotype, cell, tumor and/or disease. Administration of nitric oxide mimetics, such as low doses, is sufficient to increase, restore or maintain nitric oxide-mediated signaling in cells so that malignant cell phenotypes, cells, tumors and/or diseases are inhibited or prevented. These methods and formulations are particularly useful in treating and preventing cancer in animals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.